MYC Associated Factor X (MAX) Peptide
MAX
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979856
Quick Overview for MYC Associated Factor X (MAX) Peptide (ABIN979856)
Target
MAX
(MYC Associated Factor X (MAX))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAX antibody (Catalog #: ARP38145_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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MYC Associated Factor X (MAX) peptide
MAX Reactivity: Human, Mouse, Rat, Cow, Dog Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAX (MYC Associated Factor X (MAX))
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Background
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MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full length nature for some of them is unknown.
Alias Symbols: orf1, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8
Protein Interaction Partner: MSH2,MXD1,MXI1,MYC,CASP5,CASP7,CSNK2A1,EPAS1,HIF1A,MAD1L1,MAPK14,MAX,MNT,MSH2,MXD1,MXD3,MXD4,MYC,MYCL1,MYCN,PLEKHF2,SMAD3,SMAD4,SNIP1,SPAG9,TEAD1,TRRAP,EP400,KAT2A,KDM5C,MAD1L1,MAX,MNT,MSH2,MXD1,MXD3,MXD4,MXI1,MYC,MYCL1,MYCN,PLEKHF2,SMAD3,SMAD4,SPAG9,TEAD1,TRRAP,ZBTB17
Protein Size: 160 -
Molecular Weight
- 18 kDa
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Gene ID
- 4149
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NCBI Accession
- NM_002382, NP_002373
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UniProt
- P61244
Target
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