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Melanocortin 4 Receptor (MC4R) (N-Term) Peptide

MC4R Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN979883
  • Target See all MC4R products
    MC4R (Melanocortin 4 Receptor (MC4R))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    VNSTHRGMHT SLHLWNRSSY RLHSNASESL GKGYSDGGCY EQLFVSPEVF
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-MC4R Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MC4R (Melanocortin 4 Receptor (MC4R))
    Background
    The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.

    Alias Symbols: MGC126851, MGC138197

    Protein Interaction Partner: ADRBK1,AGRP,ASIP,ATRNL1,MC1R,NPY,POMC,PRKACA,AGRP,ATRNL1,MGRN1,POMC

    Protein Size: 332
    Molecular Weight
    37 kDa
    Gene ID
    4160
    NCBI Accession
    NM_005912, NP_005903
    UniProt
    P32245
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