Melanocortin 4 Receptor (MC4R) (N-Term) Peptide
Quick Overview for Melanocortin 4 Receptor (MC4R) (N-Term) Peptide (ABIN979883)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- VNSTHRGMHT SLHLWNRSSY RLHSNASESL GKGYSDGGCY EQLFVSPEVF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MC4R Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MC4R (Melanocortin 4 Receptor (MC4R))
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Background
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The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.
Alias Symbols: MGC126851, MGC138197
Protein Interaction Partner: ADRBK1,AGRP,ASIP,ATRNL1,MC1R,NPY,POMC,PRKACA,AGRP,ATRNL1,MGRN1,POMC
Protein Size: 332 -
Molecular Weight
- 37 kDa
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Gene ID
- 4160
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NCBI Accession
- NM_005912, NP_005903
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UniProt
- P32245
Target
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