Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Peptide
MMP1
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN980147
Quick Overview for Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Peptide (ABIN980147)
Target
MMP1
(Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MMP1 antibody (Catalog #: ARP42040_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
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Background
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP1 is a secreted enzyme which breaks down the interstitial collagens, types I, II, and III.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Alias Symbols: CLG, CLGN
Protein Interaction Partner: F2R,ACAN,BCAN,BSG,CCL13,CCL2,CCL7,CD44,CMA1,COL2A1,IGFBP3,ITGA2,MMP7,SERPINA3,TFPI,TIMP1,TNFSF11,BCAN,BSG,ITGA2,TIMP1
Protein Size: 469 -
Molecular Weight
- 52 kDa
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Gene ID
- 4312
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NCBI Accession
- NM_002421, NP_002412
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UniProt
- P03956
Target
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