MNAT CDK-Activating Kinase Assembly Factor 1 (MNAT1) Peptide
MNAT1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980168
Quick Overview for MNAT CDK-Activating Kinase Assembly Factor 1 (MNAT1) Peptide (ABIN980168)
Target
MNAT1
(MNAT CDK-Activating Kinase Assembly Factor 1 (MNAT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MNAT1 antibody (Catalog #: ARP38150_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MNAT1 (MNAT CDK-Activating Kinase Assembly Factor 1 (MNAT1))
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Background
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Cyclin-dependent kinases (CDKs), which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase (CAK). CAK is a multisubunit protein that includes CDK7, cyclin H, and MAT1. MAT1 (for 'menage a trois-1') is involved in the assembly of the CAK complex.Cyclin-dependent kinases (CDKs), which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase (CAK). CAK is a multisubunit protein that includes CDK7 (MIM 601955), cyclin H (CCNH, MIM 601953), and MAT1. MAT1 (for 'menage a trois-1') is involved in the assembly of the CAK complex.[supplied by OMIM].
Alias Symbols: MAT1, TFB3, CAP35, RNF66
Protein Interaction Partner: MTA1,BRCA1,C1orf103,C7orf64,CDK7,COPS6,E2F1,EEF1A1,ERCC3,ESR1,GTF2E2,HPS6,MCM7,MTA1,POU2F1,POU2F2,POU5F1,RB1,TP53,C1orf103,C7orf64,CCNH,CDK7,COPS6,EEF1A1,ERCC3,ESR1,HPS6,MCM7,MTA1,POU2F1,POU2F2,POU5F1,RB1,TP53
Protein Size: 309 -
Molecular Weight
- 36 kDa
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Gene ID
- 4331
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NCBI Accession
- NM_002431, NP_002422
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UniProt
- P51948
Target
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