MNT, MAX Dimerization Protein (MNT) (N-Term) Peptide
MNT
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980172
$160.46
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100 μg
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Quick Overview for MNT, MAX Dimerization Protein (MNT) (N-Term) Peptide (ABIN980172)
Target
MNT
(MNT, MAX Dimerization Protein (MNT))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MNT antibody (Catalog #: ARP39412_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MNT (MNT, MAX Dimerization Protein (MNT))
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Background
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The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. MNT is a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MAD6, MXD6, ROX, bHLHd3
Protein Interaction Partner: HMGB1,MAX,MLX,MNT,SIN3A,MAX,MLX,MNT,SIN3A,Sin3a
Protein Size: 582 -
Molecular Weight
- 62 kDa
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Gene ID
- 4335
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NCBI Accession
- NM_020310, NP_064706
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UniProt
- Q99583
Target
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