Mitochondrial Ribosomal Protein L10 (MRPL10) (N-Term) Peptide
MRPL10
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980240
Quick Overview for Mitochondrial Ribosomal Protein L10 (MRPL10) (N-Term) Peptide (ABIN980240)
Target
MRPL10
(Mitochondrial Ribosomal Protein L10 (MRPL10))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MRPL10 antibody (Catalog #: ARP52830_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MRPL10 (Mitochondrial Ribosomal Protein L10 (MRPL10))
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Background
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 5q. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 5q.
Alias Symbols: MGC17973, MRP-L8, RPML8, L10MT, MRPL8, MRP-L10
Protein Interaction Partner: MRPL10,USP22
Protein Size: 261 -
Molecular Weight
- 29 kDa
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Gene ID
- 124995
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NCBI Accession
- NM_145255, NP_660298
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UniProt
- Q7Z7H8
Target
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