Mitochondrial Ribosomal Protein L3 (MRPL3) (N-Term) Peptide
MRPL3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980251
Quick Overview for Mitochondrial Ribosomal Protein L3 (MRPL3) (N-Term) Peptide (ABIN980251)
Target
MRPL3
(Mitochondrial Ribosomal Protein L3 (MRPL3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MPLWTKDGQK HVVTLLQVQD CHVLKYTSKE NCNGKMATLS VGGKTVSRFR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MRPL3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Mitochondrial Ribosomal Protein L3 (MRPL3) peptide
MRPL3 Reactivity: Human, Cow, Pig Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MRPL3 (Mitochondrial Ribosomal Protein L3 (MRPL3))
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Background
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q.
Alias Symbols: MRL3, RPML3
Protein Interaction Partner: ICT1
Protein Size: 348 -
Molecular Weight
- 38 kDa
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Gene ID
- 11222
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NCBI Accession
- NM_007208, NP_009139
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UniProt
- P09001
Target
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