Metastasis Associated 1 (MTA1) Peptide
MTA1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980316
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Metastasis Associated 1 (MTA1) Peptide (ABIN980316)
Target
MTA1
(Metastasis Associated 1 (MTA1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MTA1 antibody (Catalog #: ARP37738_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Metastasis Associated 1 (MTA1) peptide
MTA1 Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MTA1 (Metastasis Associated 1 (MTA1))
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Background
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MTA1 encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. MTA1 was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.
Protein Interaction Partner: BLOC1S1,ITGB3BP,MNAT1,BLOC1S1,CCNH,DDX18,DYNLL1,ESR1,GPR183,GRB2,HDAC1,HDAC2,HIF1A,ITGB3BP,MNAT1,RBBP4,SH3GLB1,TH1L,TP53,ATR,CCNH,CDK7,CHD4,ESR1,FOXP1,GPR183,HDAC1,HDAC2,HIF1A,MBD3L1,MNAT1,MTA1,MTA2,NAA10,RBBP4,RBBP7,SIN3A,TH1L,TP53
Protein Size: 430 -
Molecular Weight
- 47 kDa
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Gene ID
- 9112
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NCBI Accession
- NM_001203258
Target
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