Melatonin Receptor 1B (MTNR1B) (N-Term) Peptide
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- Target See all Melatonin Receptor 1B (MTNR1B) products
- Melatonin Receptor 1B (MTNR1B)
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SFANCCEAGG WAVRPGWSGA GSARPSRTPR PPWVAPALSA VLIVTTAVDV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MTNR1B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Melatonin Receptor 1B (MTNR1B)
- Background
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This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
Alias Symbols: FGQTL2, MEL-1B-R, MT2
Protein Size: 362 - Molecular Weight
- 40 kDa
- Gene ID
- 4544
- NCBI Accession
- NM_005959, NP_005950
- UniProt
- P49286
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