Mitochondrial Translational Release Factor 1-Like (MTRF1L) (N-Term) Peptide
MTRF1L
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MTRF1L products
- MTRF1L (Mitochondrial Translational Release Factor 1-Like (MTRF1L))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MRSRVLWGAA RWLWPRRAVG PARRPLSSGS PPLEELFTRG GPLRTFLERQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RF1ML Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MTRF1L (Mitochondrial Translational Release Factor 1-Like (MTRF1L))
- Background
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The protein encoded by this gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA. This protein acts upon UAA and UAG stop codons, but has no in vitro activity against UGA, which encodes tryptophan in human mitochondrion, or, the mitochondrial non-cognate stop codons, AGA and AGG. This protein shares sequence similarity to bacterial release factors. Pseudogenes of this gene are found on chromosomes 4, 8, and 11. Alternative splicing results in multiple transcript variants.
Alias Symbols: MRF1L, HMRF1L, mtRF1a
Protein Size: 271 - Molecular Weight
- 30 kDa
- Gene ID
- 54516
- NCBI Accession
- NM_001114184, NP_001107656
- UniProt
- Q9UGC7
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