MAX Dimerization Protein 4 (MXD4) Peptide
MXD4
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all MXD4 products
- MXD4 (MAX Dimerization Protein 4 (MXD4))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MXD4 antibody (Catalog #: ARP32777_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MXD4 (MAX Dimerization Protein 4 (MXD4))
- Background
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MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Alias Symbols: MAD4, MST149, MSTP149, bHLHc12
Protein Interaction Partner: MAX,MLX,SHBG,SIN3A,TCP10L,MAX,MLX,SMC3,TCP10L
Protein Size: 209 - Molecular Weight
- 24 kDa
- Gene ID
- 10608
- NCBI Accession
- NM_006454, NP_006445
- UniProt
- Q14582
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