MAX Dimerization Protein 4 (MXD4) Peptide
MXD4
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN980397
Quick Overview for MAX Dimerization Protein 4 (MXD4) Peptide (ABIN980397)
Target
MXD4
(MAX Dimerization Protein 4 (MXD4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MXD4 antibody (Catalog #: ARP32777_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MXD4 (MAX Dimerization Protein 4 (MXD4))
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Background
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MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Alias Symbols: MAD4, MST149, MSTP149, bHLHc12
Protein Interaction Partner: MAX,MLX,SHBG,SIN3A,TCP10L,MAX,MLX,SMC3,TCP10L
Protein Size: 209 -
Molecular Weight
- 24 kDa
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Gene ID
- 10608
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NCBI Accession
- NM_006454, NP_006445
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UniProt
- Q14582
Target
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