MYST Histone Acetyltransferase 2 (MYST2) (N-Term) Peptide
MYST2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980455
$160.46
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100 μg
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Quick Overview for MYST Histone Acetyltransferase 2 (MYST2) (N-Term) Peptide (ABIN980455)
Target
MYST2
(MYST Histone Acetyltransferase 2 (MYST2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MYST2 antibody (Catalog #: ARP31518_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MYST2 (MYST Histone Acetyltransferase 2 (MYST2))
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Background
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MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly.
Alias Symbols: HBO1, HBOA, KAT7, MYST2
Protein Interaction Partner: AR,ATN1,BARD1,C15orf29,C9orf82,CALCOCO2,CBX8,CDK11A,CDK11B,CEP70,DDX11,DVL3,HOOK2,ING4,KCTD13,KIAA1377,MCM2,NINL,ORC1L,PACSIN1,POLB,PPID,RGL2,RPS10,SAT1,SEPT5,SNAPIN,VIM,WDR33,ZBTB8B,ZNF165,AR,ATN1,C15orf29,C9orf82,CALCOCO2,CBX8,CEP70,DDX11,DVL3,HIST1H4A,HOOK2,ING4,ING5,KCTD13,MEAF6,NINL,ORC1L,PACSIN1,PHF15,PHF16,PHF17,POLB,PPID,RGL2,RPS10,SAT1,SEPT5,SNAPIN,TP53,VIM,WDR33,ZBTB8A,ZNF165
Protein Size: 611 -
Molecular Weight
- 71 kDa
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Gene ID
- 11143
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NCBI Accession
- NM_007067, NP_008998
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UniProt
- O95251
Target
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