NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) Peptide
Quick Overview for NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) Peptide (ABIN980469)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NAB2 antibody (Catalog #: ARP38716_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))
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Background
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NAB2 is a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize withThis gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MADER, MGC75085
Protein Interaction Partner: EGR1,EGR1
Protein Size: 525 -
Molecular Weight
- 56 kDa
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Gene ID
- 4665
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NCBI Accession
- NM_005967, NP_005958
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UniProt
- Q15742
Target
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