N-Acetylglutamate Synthase (NAGS) Peptide
NAGS
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980473
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for N-Acetylglutamate Synthase (NAGS) Peptide (ABIN980473)
Target
NAGS
(N-Acetylglutamate Synthase (NAGS))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NAGS antibody (Catalog #: ARP51183_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NAGS (N-Acetylglutamate Synthase (NAGS))
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Background
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NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
Alias Symbols: AGAS, ARGA, MGC133025
Protein Interaction Partner: TMEM39B
Protein Size: 534 -
Molecular Weight
- 58 kDa
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Gene ID
- 162417
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NCBI Accession
- NM_153006, NP_694551
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UniProt
- Q8N159
Target
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