N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2) Peptide
NAT2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980503
Quick Overview for N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2) Peptide (ABIN980503)
Target
NAT2
(N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NAT2 antibody (Catalog #: ARP44195_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NAT2 (N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))
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Background
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NAT2 is a N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in its gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.This gene encodes N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near NAT2.
Alias Symbols: AAC2, PNAT
Protein Interaction Partner: NAA10
Protein Size: 290 -
Molecular Weight
- 32 kDa
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Gene ID
- 10
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NCBI Accession
- NM_000015, NP_000006
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UniProt
- P11245
Target
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