Neural Cell Adhesion Molecule 1 (NCAM1) (C-Term) Peptide
NCAM1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980513
Quick Overview for Neural Cell Adhesion Molecule 1 (NCAM1) (C-Term) Peptide (ABIN980513)
Target
CD56 (NCAM1)
(Neural Cell Adhesion Molecule 1 (NCAM1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- AFFAKSAAIY NPVIYIMMNK QFRNCMLTTI CCGKNPLGDD EASATVSKTE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NCAM1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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Background
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Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
Alias Symbols: CD56, MSK39, NCAM
Protein Interaction Partner: ADRBK1,ARR3,GNGT1,GRK1,GRK5,GRK6,PPP2CA,PRKCA,SAG,ADRBK1,ARR3,GRK1,GRK5,RHO,SAG,UBC
Protein Size: 348 -
Molecular Weight
- 39 kDa
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Gene ID
- 4684
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NCBI Accession
- NM_181351, NP_851996
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UniProt
- P13591
Target
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