Nucleolin (NCL) Peptide
Quick Overview for Nucleolin (NCL) Peptide (ABIN980529)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NCL antibody (Catalog #: ARP40583_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Nucleolin (NCL)
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Background
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Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus.Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
Alias Symbols: C23
Protein Interaction Partner: ECs4559,HCVgp1,TOP1,MYC,TERT,ADAP1,CD3E,CDKN2A,CSNK2A1,CSNK2A2,FMR1,GZMA,MDK,MYB,MYBL1,NDRG1,NPM1,NR3C1,PARP1,PPARGC1A,PPM1D,PRKCZ,S100A11,SFRS12,SSB,STAU1,TERT,TOP1,TP53,ZNF689,ADAP1,CD3E,CSNK2A2,CYFIP1,FMR1,MDK,MYB,MYBL1,NPM1,NR3C1,PPP1CB,PRKCZ,RECQL5,RRP1B,Rrp1b,S100A11,SP1,SSB,SWAP70,TERT,TOP1,TP53
Protein Size: 710 -
Molecular Weight
- 78 kDa
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Gene ID
- 4691
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NCBI Accession
- NM_005381, NP_005372
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UniProt
- P19338
Target
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