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N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4) Peptide

NDST4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN980559

Quick Overview for N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4) Peptide (ABIN980559)

Target

NDST4 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4))

Origin

Human

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-NDST4 antibody (Catalog #: ARP49737_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    NDST4 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4))

    Background

    NDST4 is an essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. It modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. NDST4 has low deacetylase activity but high sulfotransferase activity.

    Alias Symbols: NDST-4, NHSST4

    Protein Size: 872

    Molecular Weight

    101 kDa

    Gene ID

    64579

    NCBI Accession

    NM_022569, NP_072091

    UniProt

    Q9H3R1
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