N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (N-Term) Peptide
NECAB3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980588
Quick Overview for N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) (N-Term) Peptide (ABIN980588)
Target
NECAB3
(N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MACAGLLTVC LLRPPAPQPQ PQTPRHPQLA PDPGPAGHTL FQDVFRRADK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NECAB3 Antibody(ARP57669_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
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Background
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The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: APBA2BP, EFCBP3, NIP1, STIP3, SYTIP2, XB51, dJ63M2.4, dJ63M2.5
Protein Interaction Partner: APBA2,APP,APBA2,IKBKG
Protein Size: 396 -
Molecular Weight
- 44 kDa
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Gene ID
- 63941
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NCBI Accession
- NM_031232, NP_112509
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UniProt
- Q96P71
Target
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