Endonuclease VIII-Like 1 (NEIL1) (C-Term) Peptide
Quick Overview for Endonuclease VIII-Like 1 (NEIL1) (C-Term) Peptide (ABIN980598)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- SLQDRHGRTI WFQGDPGPLA PKGRKSRKKK SKATQLSPED RVEDALPPSK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NEIL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
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Background
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NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
Alias Symbols: FLJ22402, FPG1, NEI1, hFPG1
Protein Size: 390 -
Molecular Weight
- 44 kDa
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Gene ID
- 79661
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NCBI Accession
- NM_024608, NP_078884
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UniProt
- Q96FI4
Target
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