NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (Middle Region) Peptide
NQO1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980861
Quick Overview for NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (Middle Region) Peptide (ABIN980861)
Target
NQO1
(NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- AILKGWFERV FIGEFAYTYA AMYDKGPFRS KKAVLSITTG GSGSMYSLQG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NQO1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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NAD(P)H Dehydrogenase, Quinone 1 (NQO1) peptide
NQO1 Reactivity: Human, Dog, Mouse, Pig, Rat Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
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Background
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This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: DHQU, DIA4, DTD, NMOR1, NMORI, QR1
Protein Interaction Partner: DNAJB1,HSPA1A,NQO1,TP53,HSPA4,ING1,NQO1
Protein Size: 274 -
Molecular Weight
- 31 kDa
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Gene ID
- 1728
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NCBI Accession
- NM_000903, NP_000894
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UniProt
- P15559
Target
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