Nuclear Mitotic Apparatus Protein 1 (NUMA1) Peptide
NUMA1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981033
Quick Overview for Nuclear Mitotic Apparatus Protein 1 (NUMA1) Peptide (ABIN981033)
Target
NUMA1
(Nuclear Mitotic Apparatus Protein 1 (NUMA1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NUMA1 antibody (Catalog #: ARP50532_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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Background
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NuMA is a structural element in maintaining nuclear integrity. A critical spindle pole-associated mechanism, called the END (Emi1/NuMA/dynein-dynactin) network, spatially restricts APC/C activity in early mitosis. The entire coding region and exon-intron boundaries of NuMa were screened in 92 familial breast cancer patients. But the results do not support the role of NuMA variants as breast cancer susceptibility alleles.
Alias Symbols: NUMA
Protein Interaction Partner: GNAI1,GPSM2,ACTR1A,EPB41,EPB41L1,EPB41L2,GNAI1,GPSM2,NCOA6,PIM1,RAD21,SMC1A,TNKS,YEATS4,ACTR1A,EPB41,EPB41L1,EPB41L2,GPSM2,NCOA6,NPM1,PIM1,RPAP1,SMC1A,SMC3,TNKS,YEATS4
Protein Size: 2115 -
Molecular Weight
- 238 kDa
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Gene ID
- 4926
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NCBI Accession
- NM_006185, NP_006176
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UniProt
- Q14980
Target
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