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NUP100 (nucleoporin 100kDa) (NUP100) Peptide

NUP100 Reactivity: Human Host: Synthetic BP, ICC, WB
Catalog No. ABIN981035

Quick Overview for NUP100 (nucleoporin 100kDa) (NUP100) Peptide (ABIN981035)

Target

NUP100 (NUP100 (nucleoporin 100kDa) (NUP100))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Immunocytochemistry (ICC), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-NUP50 antibody (Catalog #: ARP52288_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    NUP100 (NUP100 (nucleoporin 100kDa) (NUP100))

    Background

    The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import.The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: MGC39961, NPAP60, NPAP60L

    Protein Interaction Partner: CDKN1B,KPNA2,KPNB1,RAN,XPO1,BTBD12,CDKN1B,IPO13,KPNA2,KPNB1,NUP153

    Protein Size: 468

    Molecular Weight

    50 kDa

    Gene ID

    10762

    NCBI Accession

    NM_007172, NP_009103

    UniProt

    Q9UKX7
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