Nucleoporin 155kDa (NUP155) (N-Term) Peptide
NUP155
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981037
Quick Overview for Nucleoporin 155kDa (NUP155) (N-Term) Peptide (ABIN981037)
Target
NUP155
(Nucleoporin 155kDa (NUP155))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- CCVMRYTTAG QLWNIISPRE FVDFSYTVGY KEGLLSCGIS LDWDEKRPEF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NUP155 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NUP155 (Nucleoporin 155kDa (NUP155))
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Background
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Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
Alias Symbols: KIAA0791, N155
Protein Size: 205 -
Molecular Weight
- 23 kDa
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Gene ID
- 9631
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NCBI Accession
- NM_004298, NP_004289
Target
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