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Nuclear RNA Export Factor 5 (NXF5) Peptide

NXF5 Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN981056

Quick Overview for Nuclear RNA Export Factor 5 (NXF5) Peptide (ABIN981056)

Target

NXF5 (Nuclear RNA Export Factor 5 (NXF5))

Origin

Human

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-NXF5 antibody (Catalog #: ARP41062_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    NXF5 (Nuclear RNA Export Factor 5 (NXF5))

    Background

    NXF5 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. Five transcript variants that encode different isoforms have been found for this gene.

    Protein Interaction Partner: NXF1

    Protein Size: 397

    Molecular Weight

    44 kDa

    Gene ID

    55998

    NCBI Accession

    NM_032946, NP_116564

    UniProt

    Q9H1B4
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