NTF2-Related Export Protein 1 (NXT1) (N-Term) Peptide
NXT1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981065
Quick Overview for NTF2-Related Export Protein 1 (NXT1) (N-Term) Peptide (ABIN981065)
Target
NXT1
(NTF2-Related Export Protein 1 (NXT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- GTATLVWNGN AVSGQESLSE FFEMLPSSEF QISVVDCQPV HDEATPSQTT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NXT1 Antibody(ARP54919_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NXT1 (NTF2-Related Export Protein 1 (NXT1))
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Background
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The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
Alias Symbols: MTR2, P15
Protein Interaction Partner: NXF1,NXF2,NXF3,RAN,XPO1,NXF1,NXF3,XPO1
Protein Size: 140 -
Molecular Weight
- 16 kDa
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Gene ID
- 29107
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NCBI Accession
- NM_013248, NP_037380
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UniProt
- Q9UKK6
Target
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