One Cut Homeobox 1 (ONECUT1) (Middle Region) Peptide
ONECUT1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN981135
Quick Overview for One Cut Homeobox 1 (ONECUT1) (Middle Region) Peptide (ABIN981135)
Target
ONECUT1
(One Cut Homeobox 1 (ONECUT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ONECUT1 antibody (Catalog #: ARP38481_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ONECUT1 (One Cut Homeobox 1 (ONECUT1))
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Background
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ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
Alias Symbols: HNF-6, HNF6, HNF6A
Protein Interaction Partner: CREBBP,FOXA2,KAT2B,NR3C1,CREBBP,FOXA1,FOXA2,KAT2B,NR3C1
Protein Size: 465 -
Molecular Weight
- 51 kDa
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Gene ID
- 3175
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NCBI Accession
- NM_004498, NP_004489
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UniProt
- Q9UBC0
Target
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