Optic Atrophy 1 (Autosomal Dominant) (OPA1) (N-Term) Peptide
OPA1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all OPA1 products
- OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SPEETAFRAT DRGSESDKHF RKVSDKEKID QLQEELLHTQ LKYQRILERL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-OPA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))
- Background
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This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ12460, KIAA0567, MGM1, NPG, NTG, largeG
Protein Size: 924 - Molecular Weight
- 102 kDa
- Gene ID
- 4976
- NCBI Accession
- NM_130831, NP_570844
- UniProt
- E5KLK2
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