ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) Peptide
ORAI1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981195
Quick Overview for ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) Peptide (ABIN981195)
Target
ORAI1
(ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ORAI1 antibody (Catalog #: ARP50117_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
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Background
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ORAI1 belongs to the Orai family. ORAI1 (CRACM1) is a plasma membrane protein essential for store-operated calcium entry. Defects in ORAI1 are a cause of severe combined immunodeficiency with CRAC channel dysfunction (CRAC-SCID).CRACM1 is a plasma membrane protein essential for store-operated calcium entry (Vig et al., 2006 [PubMed 16645049]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-331 BC075831.1 1-331 332-844 BC013386.1 220-732 845-990 BC075831.1 845-990 991-1490 BG574128.1 52-551 1491-1496 AK027372.1 1235-1240
Alias Symbols: CRACM1, FLJ14466, TMEM142A, ORAT1
Protein Interaction Partner: TRPC3,TRPC6
Protein Size: 301 -
Molecular Weight
- 33 kDa
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Gene ID
- 84876
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NCBI Accession
- NM_032790, NP_116179
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UniProt
- Q96D31
Target
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