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Osteoclast Associated Receptor (OSCAR) (C-Term) Peptide

OSCAR Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981213

Quick Overview for Osteoclast Associated Receptor (OSCAR) (C-Term) Peptide (ABIN981213)

Target

OSCAR (Osteoclast Associated Receptor (OSCAR))

Origin

Human

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    VISWEDSGSS DYTRGNLVRL GLAGLVLISL GALVTFDWRS QNRAPAGIRP

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-OSCAR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    OSCAR (Osteoclast Associated Receptor (OSCAR))

    Background

    Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: MGC33613, PIGR3

    Protein Interaction Partner: FCAR

    Protein Size: 267

    Molecular Weight

    29 kDa

    Gene ID

    126014

    NCBI Accession

    NM_130771, NP_570127
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