Osteoclast Associated Receptor (OSCAR) (C-Term) Peptide
OSCAR
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all OSCAR products
- OSCAR (Osteoclast Associated Receptor (OSCAR))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VISWEDSGSS DYTRGNLVRL GLAGLVLISL GALVTFDWRS QNRAPAGIRP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-OSCAR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- OSCAR (Osteoclast Associated Receptor (OSCAR))
- Background
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Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC33613, PIGR3
Protein Interaction Partner: FCAR
Protein Size: 267 - Molecular Weight
- 29 kDa
- Gene ID
- 126014
- NCBI Accession
- NM_130771, NP_570127
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