Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6) Peptide
P2RX6
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981277
Quick Overview for Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6) Peptide (ABIN981277)
Target
P2RX6
(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-P2RXL1 antibody (Catalog #: ARP35173_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- P2RX6 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6))
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Background
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P2RXL1 encodes a protein in the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. P2RXL1 is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells.
Alias Symbols: P2X6, P2XM, P2RXL1
Protein Interaction Partner: CDH5
Protein Size: 431 -
Molecular Weight
- 47 kDa
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Gene ID
- 9127
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NCBI Accession
- NM_005446, NP_005437
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UniProt
- O15547
Target
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