Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) (Middle Region) Peptide
P4HA1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981286
Quick Overview for Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) (Middle Region) Peptide (ABIN981286)
Target
P4HA1
(Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- TKKLLELDPE HQRANGNLKY FEYIMAKEKD VNKSASDDQS DQKTTPKKKG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-P4HA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- P4HA1 (Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))
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Background
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This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: P4HA
Protein Size: 534 -
Molecular Weight
- 59 kDa
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Gene ID
- 5033
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NCBI Accession
- NM_000917, NP_000908
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UniProt
- P13674
Target
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