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Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) (Middle Region) Peptide

P4HA1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981287
  • Target See all P4HA1 products
    P4HA1 (Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    MAKEKDVNKS ASDDQSDQKT TPKKKGVAVD YLPERQKYEM LCRGEGIKMT
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-P4HA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    P4HA1 (Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))
    Synonyms
    P4HA Peptide, AL022634 Peptide, P4ha Peptide, PHalphaI Peptide, prolyl 4-hydroxylase subunit alpha-1 Peptide, prolyl 4-hydroxylase subunit alpha 1 Peptide, procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide Peptide, CpipJ_CPIJ000975 Peptide, CpipJ_CPIJ017131 Peptide, Tsp_03346 Peptide, Tsp_03347 Peptide, Tsp_15957 Peptide, P4HA1 Peptide, P4ha1 Peptide
    Background
    This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

    Alias Symbols: P4HA

    Protein Size: 516
    Molecular Weight
    56 kDa
    Gene ID
    5033
    NCBI Accession
    NM_001142596, NP_001136068
    UniProt
    C9JL12
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