Proliferation-Associated 2G4, 38kDa (PA2G4) Peptide
PA2G4
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN981291
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Proliferation-Associated 2G4, 38kDa (PA2G4) Peptide (ABIN981291)
Target
PA2G4
(Proliferation-Associated 2G4, 38kDa (PA2G4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PA2G4 antibody (Catalog #: ARP47601_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))
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Background
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PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells.This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EBP1, HG4-1, p38-2G4
Protein Interaction Partner: ERBB3,HDAC2,AR,ERBB3,EXOSC5,HDAC2,PRKCA,PRKCB,PRKCG,RB1,SIN3A,SUMO4,AR,ATR,ERBB3,HDAC2,MTOR,RB1,SGK1,USP39
Protein Size: 394 -
Molecular Weight
- 44 kDa
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Gene ID
- 5036
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NCBI Accession
- NM_006191, NP_006182
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UniProt
- Q9UQ80
Target
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