Proliferation-Associated 2G4, 38kDa (PA2G4) (C-Term) Peptide
PA2G4
Reactivity: Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN981293
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Proliferation-Associated 2G4, 38kDa (PA2G4) (C-Term) Peptide (ABIN981293)
Target
PA2G4
(Proliferation-Associated 2G4, 38kDa (PA2G4))
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- PDLYKSEMEV QDAELKALLQ SSASRKTQKK KKKKASKTVE NATSGETLEE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Pa2g4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))
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Background
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Pa2g4 may play a role in a ERBB3-regulated signal transduction pathway. It seems be involved in growth regulation. It acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). It inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. It may be involved in ribosome assembly. It mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site). It together with PTBP1 is required for the translation initiation on the foot-and-mouth disease virus (FMDV) IRES.
Alias Symbols: 38 kDa, AA672939, Ebp1, Plfap
Protein Size: 394 -
Molecular Weight
- 44 kDa
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Gene ID
- 18813
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NCBI Accession
- NM_011119, NP_035249
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UniProt
- P50580
Target
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