Par-3 Partitioning Defective 3 Homolog (PARD3) (Middle Region) Peptide
Quick Overview for Par-3 Partitioning Defective 3 Homolog (PARD3) (Middle Region) Peptide (ABIN981348)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PARD3 antibody (Catalog #: ARP42910_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))
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Background
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PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange
Alias Symbols: ASIP, Baz, Bazooka, FLJ21015, PAR3, PAR3alpha, PARD3A, SE2-5L16, SE2-5LT1, SE2-5T2
Protein Interaction Partner: PLCB1,PLCB3,CDC42,DYNLL1,F11R,INADL,INSC,LIMK2,PARD3,PARD6A,PARD6B,PARD6G,PLCB1,PLCB3,PNMA1,PRKCG,PRKCI,PVRL1,PVRL3,SMAD2,SMAD3,SMAD4,SMAD7,STK11,TIAM1,TIAM2,YWHAB,YWHAG,YWHAH,YWHAZ,ECT2,F11R,JAM2,JAM3,PARD6A,PARD6B,PARD6G,PRKCI,PRKCZ,PVRL3,SFN,YWHAB,YWHAG
Protein Size: 1356 -
Molecular Weight
- 151 kDa
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Gene ID
- 56288
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NCBI Accession
- NM_019619, NP_062565
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UniProt
- Q8TEW0
Target
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