Parkinson Protein 7 (PARK7) (C-Term) Peptide
PARK7
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN981353
Quick Overview for Parkinson Protein 7 (PARK7) (C-Term) Peptide (ABIN981353)
Target
PARK7/DJ1 (PARK7)
(Parkinson Protein 7 (PARK7))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Protein Region
- C-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PARK7 antibody (Catalog #: ARP51267_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
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Background
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PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7.The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: DJ-1, DJ1, FLJ27376
Protein Interaction Partner: DAXX,EFCAB6,PARK7,PIAS2,PPP2R1A,PPP2R1B,SUMO1,C19orf62,EFCAB6,PIAS2,USP19
Protein Size: 189 -
Molecular Weight
- 20 kDa
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Gene ID
- 11315
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NCBI Accession
- NM_007262, NP_009193
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UniProt
- Q99497
Target
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