Paired Box 5 (PAX5) Peptide
PAX5
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN981389
Quick Overview for Paired Box 5 (PAX5) Peptide (ABIN981389)
Target
PAX5
(Paired Box 5 (PAX5))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PAX5 antibody (Catalog #: ARP34686_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PAX5 (Paired Box 5 (PAX5))
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Background
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The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
Alias Symbols: BSAP
Protein Interaction Partner: CREBBP,DAXX,CREBBP,DAXX,EBF1,ETS1,ID2,ID3,KPNA1,KPNA2,MYB,PAX5,RB1,RUNX1,TBP,TLE4,DAXX,ID3,MYB,RUNX1,TLE4
Protein Size: 391 -
Molecular Weight
- 42 kDa
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Gene ID
- 5079
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NCBI Accession
- NM_016734, NP_057953
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UniProt
- Q02548
Target
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