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Nicotinamide phosphoribosyltransferase (NAMPT) Peptide

NAMPT Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN981404

Quick Overview for Nicotinamide phosphoribosyltransferase (NAMPT) Peptide (ABIN981404)

Target

NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Origin

Human

Source

  • 6
Synthetic

Application

Western Blotting (WB), Blocking Peptide (BP)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-PBEF1 antibody (Catalog #: ARP42254_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

    Background

    PBEF1 catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

    Alias Symbols: 1110035O14Rik, DKFZP666B131, MGC117256, NAMPT, PBEF, VF, PBEF1, VISFATIN

    Protein Interaction Partner: FANCA

    Protein Size: 491

    Molecular Weight

    54 kDa

    Gene ID

    10135

    NCBI Accession

    NM_005746, NP_005737

    UniProt

    P43490
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