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Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) Peptide

PBX1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981410
  • Target See all PBX1 products
    PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PBX1 antibody (Catalog #: ARP30948_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
    Background
    PBX1 binds the sequence 5'-ATCAATCAA-3'. It acts as a transcriptional activator of PF4 in complex with MEIS1. It may be converted into a potent transcriptional activator by the (1,19) translocation. It also may have a role in steroidogenesis and, subsequently, sexual development and differentiation.

    Alias Symbols: DKFZp686B09108, MGC126627

    Protein Interaction Partner: PAX6,HOXA10,HOXA5,HOXA9,HOXB1,HOXB8,HOXD10,HOXD4,MEIS1,MYH10,NR3C1,PAX6,PBX2,PKNOX1,SMARCD3,HOXA9,HOXB1,HOXB7,HOXB8,HOXD4,HOXD9,MEIS1,MYH10,MYOD1,Myh10,NR3C1,PKNOX1

    Protein Size: 430
    Molecular Weight
    47 kDa
    Gene ID
    5087
    NCBI Accession
    NM_002585, NP_002576
    UniProt
    P40424
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