Protocadherin-15 (PCDH15) Peptide
PCDH15
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981439
Quick Overview for Protocadherin-15 (PCDH15) Peptide (ABIN981439)
Target
PCDH15
(Protocadherin-15 (PCDH15))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PCDH15 antibody (Catalog #: ARP50153_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PCDH15 (Protocadherin-15 (PCDH15))
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Background
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PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.
Alias Symbols: RP11-449J3.2, DFNB23, DKFZp667A1711, USH1F, CDHR15
Protein Size: 719 -
Molecular Weight
- 80 kDa
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Gene ID
- 65217
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NCBI Accession
- NM_001142763
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UniProt
- A2A3E5
Target
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