Protocadherin-15 (PCDH15) Peptide
PCDH15
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PCDH15 products
- PCDH15 (Protocadherin-15 (PCDH15))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PCDH15 antibody (Catalog #: ARP50153_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PCDH15 (Protocadherin-15 (PCDH15))
- Synonyms
- CDHR15 Peptide, DFNB23 Peptide, USH1F Peptide, BB078305 Peptide, ENSMUSG00000046980 Peptide, Gm9815 Peptide, Ush1f Peptide, av Peptide, nmf19 Peptide, protocadherin-15 Peptide, protocadherin related 15 Peptide, protocadherin-15 Peptide, protocadherin 15 Peptide, PCDH15 Peptide, CpipJ_CPIJ005081 Peptide, Pcdh15 Peptide
- Background
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PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.
Alias Symbols: RP11-449J3.2, DFNB23, DKFZp667A1711, USH1F, CDHR15
Protein Size: 719 - Molecular Weight
- 80 kDa
- Gene ID
- 65217
- NCBI Accession
- NM_001142763
- UniProt
- A2A3E5
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