Protocadherin beta 16 (PCDHB16) (Middle Region) Peptide
Quick Overview for Protocadherin beta 16 (PCDHB16) (Middle Region) Peptide (ABIN981458)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- IPENSPLGSL VATVSARDLD GGANGKISYT LFQPSEDISK TLEVNPMTGE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PCDHB16 Antibody(ARP49598_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PCDHB16 (Protocadherin beta 16 (PCDHB16))
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Background
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This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Alias Symbols: KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a
Protein Size: 776 -
Molecular Weight
- 82 kDa
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Gene ID
- 57717
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NCBI Accession
- NM_020957, NP_066008
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UniProt
- Q9NRJ7
Target
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