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Protocadherin beta 16 (PCDHB16) (Middle Region) Peptide

PCDHB16 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981458
$160.46
Plus shipping costs $50.00
100 μg
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Quick Overview for Protocadherin beta 16 (PCDHB16) (Middle Region) Peptide (ABIN981458)

Target

PCDHB16 (Protocadherin beta 16 (PCDHB16))

Origin

Human

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequence

    IPENSPLGSL VATVSARDLD GGANGKISYT LFQPSEDISK TLEVNPMTGE

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-PCDHB16 Antibody(ARP49598_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PCDHB16 (Protocadherin beta 16 (PCDHB16))

    Background

    This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

    Alias Symbols: KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a

    Protein Size: 776

    Molecular Weight

    82 kDa

    Gene ID

    57717

    NCBI Accession

    NM_020957, NP_066008

    UniProt

    Q9NRJ7
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