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Protocadherin beta 16 (PCDHB16) (Middle Region) Peptide

PCDHB16 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981458
  • Target See all PCDHB16 products
    PCDHB16 (Protocadherin beta 16 (PCDHB16))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    IPENSPLGSL VATVSARDLD GGANGKISYT LFQPSEDISK TLEVNPMTGE
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PCDHB16 Antibody(ARP49598_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PCDHB16 (Protocadherin beta 16 (PCDHB16))
    Synonyms
    ME1 Peptide, PCDH-BETA16 Peptide, PCDH3X Peptide, PCDHB8a Peptide, Pcdhb8 Peptide, PcdhbP Peptide, PCDHB16 Peptide, Pcdhb8a Peptide, PCDHB8 Peptide, protocadherin beta 16 Peptide, protocadherin beta-16 Peptide, protocadherin beta 6 Peptide, PCDHB16 Peptide, Pcdhb16 Peptide, LOC100848138 Peptide, LOC100349989 Peptide, PCDHB6 Peptide
    Background
    This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

    Alias Symbols: KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a

    Protein Size: 776
    Molecular Weight
    82 kDa
    Gene ID
    57717
    NCBI Accession
    NM_020957, NP_066008
    UniProt
    Q9NRJ7
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