Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6) Peptide
PCSK6
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981484
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6) Peptide (ABIN981484)
Target
PCSK6
(Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PCSK6 antibody (Catalog #: ARP57880_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
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Background
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PCSK6 is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. This gene is thought to play a role in tumor progression.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: PACE4, SPC4
Protein Interaction Partner: FLG,PCSK6,PMCH,RCN3
Protein Size: 975 -
Molecular Weight
- 91 kDa
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Gene ID
- 5046
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NCBI Accession
- NM_138320, NP_612193
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UniProt
- Q63415
Target
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