phosphodiesterase 11A (PDE11A) (N-Term) Peptide
PDE11A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PDE11A products
- PDE11A (phosphodiesterase 11A (PDE11A))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RRASQKELRK SFARSKAIHV NRTYDEQVTS RAQEPLSSVR RRALLRKASS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PDE11A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PDE11A (phosphodiesterase 11A (PDE11A))
- Background
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The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ23693, MGC133355, MGC133356, PPNAD2
Protein Size: 933 - Molecular Weight
- 105 kDa
- Gene ID
- 50940
- NCBI Accession
- NM_016953, NP_058649
- UniProt
- Q9HCR9
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