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Phosphatidylethanolamine N-Methyltransferase (PEMT) Peptide

PEMT Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981582

Quick Overview for Phosphatidylethanolamine N-Methyltransferase (PEMT) Peptide (ABIN981582)

Target

PEMT (Phosphatidylethanolamine N-Methyltransferase (PEMT))

Origin

Human

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-PEMT antibody (Catalog #: ARP43558_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PEMT (Phosphatidylethanolamine N-Methyltransferase (PEMT))

    Background

    PEMT is an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene encodes PEMT protein is within the Smith-Magenis syndrome region on chromosome 17. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.

    Alias Symbols: MGC2483, PEAMT, PEMPT, PEMT2, PNMT

    Protein Size: 236

    Molecular Weight

    26 kDa

    Gene ID

    10400

    NCBI Accession

    NM_148172, NP_680477

    UniProt

    Q9BW86
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