Peroxisomal Biogenesis Factor 19 (PEX19) (C-Term) Peptide
PEX19
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981599
Quick Overview for Peroxisomal Biogenesis Factor 19 (PEX19) (C-Term) Peptide (ABIN981599)
Target
PEX19
(Peroxisomal Biogenesis Factor 19 (PEX19))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- AETPTDSETT QKARFEMVLD LMQQLQDLGH PPKELAGEMP PGLNFDLDAL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PEX19 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))
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Background
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This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
Alias Symbols: D1S2223E, FLJ55296, HK33, PMP1, PMPI, PXF, PXMP1
Protein Interaction Partner: ABCD1,ABCD2,ABCD3,PEX10,PEX11B,PEX12,PEX13,PEX14,PEX16,PEX3,ABCD1,ABCD2,ABCD3,CDKN2A,PEX10,PEX11A,PEX11B,PEX12,PEX13,PEX14,PEX16,PEX3,PMP22,PXMP4,SLC25A17,SLC34A1,SMAD2,ABCD1,ABCD2,ABCD3,PEX10,PEX11B,PEX12,PEX13,PEX14,PEX16,PEX3,SLC25A17
Protein Size: 299 -
Molecular Weight
- 33 kDa
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Gene ID
- 5824
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NCBI Accession
- NM_002857, NP_002848
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UniProt
- P40855
Target
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