Progesterone Receptor (PGR) (N-Term) Peptide
PGR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981652
$160.46
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100 μg
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Quick Overview for Progesterone Receptor (PGR) (N-Term) Peptide (ABIN981652)
Target
Progesterone Receptor (PGR)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PGR antibody (Catalog #: ARP38005_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Progesterone Receptor (PGR)
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Background
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This protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NR3C3, PR
Protein Interaction Partner: ESR1,ESR1,HIST3H3,HIST3H3,HIST4H4,HIST4H4,SP1,SP1,BCAS2,KAT2B,PRMT2,RBM23,RBM39,APEX2,BATF3,BCAS2,CCNA2,CSNK2A1,CUEDC2,DDX54,ESR1,FKBP5,HMGB2,JDP2,KLF9,NCOA1,NCOA3,PGR,PIAS1,PIAS3,POU2F1,PRMT2,RBM23,RBM39,RELA,SNW1,SORBS1,SRC,TRIM24,UBE3A,UBR5,XRCC6,ZBTB17,CDC25B,CUEDC2,DAP3,DDX54,FKBP5,HMGB1,HMGB2,KLF9,KLF9,NCOA1,NCOA3,NCOR2,Ncoa2,PIAS2,POU2F1,POU2F2,RELA,RNF4,SMARCD1,TDG,UBE3A,UBR5
Protein Size: 933 -
Molecular Weight
- 99 kDa
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Gene ID
- 5241
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NCBI Accession
- NM_000926, NP_000917
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UniProt
- P06401
Target
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