Polyhomeotic Homolog 2 (Drosophila) (PhC2) (N-Term) Peptide
PhC2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981668
$160.46
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100 μg
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Quick Overview for Polyhomeotic Homolog 2 (Drosophila) (PhC2) (N-Term) Peptide (ABIN981668)
Target
PHC2 (PhC2)
(Polyhomeotic Homolog 2 (Drosophila) (PhC2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- GGSGRPTGPQ ISVYSGIPDR QTVQVIQQAL HRQPSTAAQY LQQMYAAQQQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PHC2 Antibody(ARP51251_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))
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Background
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In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EDR2, HPH2, MGC163502, PH2
Protein Interaction Partner: MAPKAPK3,AFG3L2,BMI1,BSDC1,FHL3,GFI1B,LMO3,MAPKAPK2,MCM2,MCRS1,PHC1,PHC2,RPL7,SCMH1,SFMBT1,TMEM70,AFG3L2,BMI1,BSDC1,Bmi1,Cbx2,FHL3,LMO3,MAPKAPK2,MCM2,MCRS1,PHC1,PHC2,RPL7,SCMH1,SFMBT1
Protein Size: 858 -
Molecular Weight
- 91 kDa
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Gene ID
- 1912
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NCBI Accession
- NM_198040, NP_932157
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UniProt
- Q8IXK0
Target
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