Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2) (N-Term) Peptide
PHLDA2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981703
Quick Overview for Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2) (N-Term) Peptide (ABIN981703)
Target
PHLDA2
(Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MKSPDEVLRE GELEKRSDSL FQLWKKKRGV LTSDRLSLFP ASPRARPKEL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PHLDA2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))
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Background
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This gene is one of several genes in the imprinted gene domain of 11p15.5 which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Studies of the mouse gene, however, which is also located in an imprinted gene domain, have shown that the product of this gene regulates placental growth.
Alias Symbols: BRW1C, BWR1C, HLDA2, IPL, TSSC3
Protein Size: 152 -
Molecular Weight
- 17 kDa
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Gene ID
- 7262
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NCBI Accession
- NM_003311, NP_003302
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UniProt
- Q53GA4
Target
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